Two-Photon Microscopy System
RK-20
The RK-20 is the first commercial platform for combined microscopy and focused ultrasound brain exposures. The system enables simultaneous ultrasound and 2 photon microscopy. Visualize cortical brain regions while they are exposed to characterize bioeffects in real-time. The RK-20 empowers researchers with a new tool to study the brain bioeffects of focused ultrasound. The RK-20 is intended to be integrated into an existing 2-photon microscopy platform.
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System configuration:
Unique ring-shaped transducer (1.2 MHz) with an optically transparent coverslip for attachment to the skull over a cranial window
Arbitrary function generator for continuous or burst-mode sonications
15W RF amplifier
Impedance matching electronics
Directional RF power meter for monitoring forward and reflected power of burst signals
PC, monitor, keyboard
​
The video below shows leakage of intra-vascular fluorescent dyes after focused ultrasound exposures with circulating microbubbles.
Two-Photon Microscopy System
RK-20
The RK-20 is the first commercial platform for combined microscopy and focused ultrasound brain exposures. The system enables simultaneous ultrasound and 2 photon microscopy. Visualize cortical brain regions while they are exposed to characterize bioeffects in real-time. The RK-20 empowers researchers with a new tool to study the brain bioeffects of focused ultrasound. The RK-20 is intended to be integrated into an existing 2-photon microscopy platform.
​
System configuration:
Unique ring-shaped transducer (1.2 MHz) with an optically transparent coverslip for attachment to the skull over a cranial window
Arbitrary function generator for continuous or burst-mode sonications
15W RF amplifier
Impedance matching electronics
Directional RF power meter for monitoring forward and reflected power of burst signals
PC, monitor, keyboard
​
The video below shows leakage of intra-vascular fluorescent dyes after focused ultrasound exposures with circulating microbubbles.
