Two-Photon Microscopy System
The RK-20 is the first commercial platform for combined microscopy and focused ultrasound brain exposures. The system enables simultaneous ultrasound and 2 photon microscopy. Visualize cortical brain regions while they are exposed to characterize bioeffects in real-time. The RK-20 empowers researchers with a new tool to study the brain bioeffects of focused ultrasound. The RK-20 is intended to be integrated into an existing 2-photon microscopy platform.
Unique ring-shaped transducer (1.2 MHz) with an optically transparent coverslip for attachment to the skull over a cranial window
Arbitrary function generator for continuous or burst-mode sonications
15W RF amplifier
Impedance matching electronics
Directional RF power meter for monitoring forward and reflected power of burst signals
PC, monitor, keyboard
The video below shows leakage of intra-vascular fluorescent dyes after focused ultrasound exposures with circulating microbubbles.
A unique ring transducer with an optically transparent coverslip is mounted to the skull of test subjects, enabling simultaneous ultrasound exposure and microscopy in cortical brain regions.
The RK-20 can be used for simultaneous ultrasound and optical microscopy.