Complete FUS Ecosystems for Preclinical Research

FUS Instruments provides the most advanced preclinical platforms for image-guided focused ultrasound research, from benchtop setups to high-field MRI-compatible systems. Our solutions are powered by in-house, custom-built transducers that offer precision ultrasound delivery and real-time cavitation monitoring. We provide the hardware, software, and expertise needed for breakthrough discoveries.

RK-50 | The Versatile Benchtop FUS Standard

The benchtop gold standard for high-throughput, image-guided focused ultrasound delivery in small animal models.

RK-300 | High-Throughput MRI-Compatible FUS System

An advanced, high-power platform with real-time MRI monitoring capability designed for complex therapeutic studies.

RK-20 | Compact FUS Solutions for Targeted Research

A compact, entry-level solution providing focused ultrasound precision for small-scale models.

DS-50 Water Degasser | Pure Acoustics for Consistent Results

Ensure acoustic transparency and peak performance by maintaining ultra-low dissolved gas levels in your coupling medium.

Nanobubbles | Ultrasound Contrast & Cavitation Agents

Highly stable, specialized contrast agents engineered to enhance cavitation.

The Core Features

Across all three platforms, FUS Instruments maintains a standard of precision that ensures your data is publishable and reproducible:

  • Precisely Calibrated Transducers: Every transducer comes fully calibrated, ensuring that the acoustic pressure you set in the software is exactly what is delivered to the tissue.

  • Custom RF Electronics: Each unit is paired with dedicated RF electronics, including arbitrary function generators, high-stability amplifiers, and directional power meters to monitor forward and reflected power.

  • Safety Monitoring: All systems are designed with the capability to monitor acoustic emissions, which is critical for preventing unintended tissue damage during blood-brain barrier opening.

  • Pulse Versatility: Capability to toggle between pulsed ultrasound (for BBB opening and neuromodulation) and continuous wave (for thermal ablation or hyperthermia studies).

Feature RK-20 RK-50 RK-300
Primary Use Case Entry-level / Specialized Research Benchtop Standard / High-Precision High-Field MRI Integration
Environment Benchtop Benchtop Small-bore MRI (e.g., Bruker)
Targeting Method Manual Stereotaxic 3-Axis Automated Stereotaxic 2-Axis Automated MR-Guided
Targeting Precision Sub-millimeter < 0.25 mm < 0.25 mm
MRI Compatibility Non-compatible Optional (Custom attachment) Full (Non-magnetic)
Acoustic Feedback Optional Integrated Cavitation Detectors Integrated RF Surface Coil
Transducer Type Single-element Calibrated Single-element Calibrated MR-Compatible Calibrated
Software Interface Manual Control / Basic Pulse Focal Point (Atlas-registered) Focal Point (Image-guided)
Key Advantage Cost-effective / Portable High-throughput / Turnkey Real-time MR-Thermometry

Accessories, Specialized Tools & Services

Enhance your experimental workflow with our suite of integrated tools:

Imaging Attachment (RK-50) | Real-Time Visual Guidance

Transform your RK-50 system into a dual-purpose platform. This attachment integrates high-resolution ultrasound imaging with your therapeutic focus, allowing for real-time anatomical targeting and monitoring of the focal zone during the procedure.

Custom Transducers | Tailored to Your Vision

We specialize in spherically focused transducer geometries. Our engineering team builds all transducers in-house, allowing specific resonant frequencies, focal lengths, and housing geometries without compromise.

Dissolved Oxygen Sensor | Real-Time Media Monitoring

Precision requires verification. This high-sensitivity sensor provides real-time feedback on the oxygen content of your coupling water, allowing you to validate your degassing process and ensure optimal acoustic transparency before you begin your session.

Installation and Training

Accelerated onboarding from our expert engineers to ensure your team achieves peak results from day one.

Extended Warranty

Protect your investment and minimize downtime with comprehensive long-term service and technical support.

High Quality Components

All our systems are constructed using high-quality components sourced from trusted vendors.

Ready to push the boundaries of what’s possible?

Our team of experts is ready to help you configure the perfect FUS setup for your specific research goals. Let’s build the future of non-invasive medicine together.