Stereotactic focused ultrasound system
The RK-50 is a preclinical benchtop FUS system capable of delivering precise ultrasound exposures in the rodent brain. The system is used by researchers worldwide to study applications including blood-brain barrier disruption, neuromodulation, and sonodynamic therapy.
Targeting is achieved using a digital brain atlas and stereotactic methods, or with non-invasive imaging using a custom attachment.
The RK-50 uses real-time acoustic feedback with a built-in hydrophone to ensure rigorous and repeatable studies.
Specifications
| Parameter | Value |
|---|---|
| X range Y range Z range | 50 mm 60 mm 60 mm |
| Maximum speed | 15 mm/s |
| Resolution (XY) | 0.1 mm |
| Power output (max) | 10 W (electrical) |
|
Transducer frequencies Harmonic frequencies Transducer diameter Transducer focal length |
0.5, 1.2, 1.6 MHz 1.5, 3.6, 4.8 MHz 35 mm 24.5 mm |
| Stereotactic frames |
Dual species Mouse & rat ear bars, nose cones, and spacers |
In-House Custom-Built Calibrated Transducers (TX-50)
When your research demands a unique approach, our engineering team is ready to build it.
All transducers manufactured by FUS Instruments undergo rigorous calibration and testing. Transducers are leak tested and impedance matched. They then undergo calibration at the focus in water with a calibrated needle hydrophone to measure the spatial dimensions of the pressure focus, and also to calibrate the voltage to pressure relationship. Radiation force measurements are obtained for each transducer to quantify the transducer efficiency.
Centrally located hydrophones enable passive cavitation detection.
An RF impedance matching network to 50 Ohm is supplied with each transducer and tuned to the fundamental resonant frequency. An optional third harmonic RF impedance matching network allows operation around three (3) times the fundamental frequency. The matching networks include BNC and SMA connectors in an aluminum, RF shielded enclosure.
| Model | Transducer Fo | FWHM Lateral | FWHM Axial | Hydrophone Aperture | Hydrophone F0 |
|---|---|---|---|---|---|
| TX-50-1650 | 1.65 MHz | 0.9 mm | 5.0 mm | ø9 mm | 0.825 MHz |
| TX-50-1200 | 1.20 MHz | 1.2 mm | 6.8 mm | ø9 mm | 0.600 MHz |
| TX-50-0550 | 0.55 MHz | 2.6 mm | 17.2 mm | ø9 mm | 0.825 MHz |
Ultrasound applications of the TX-50 transducer series include, but are not limited to, increasing the permeability of the blood-brain barrier, neuromodulation, sonodynamic therapy, and thermal ablation. Spherically focused TX-50 transducers have an f-number of 0.7 and 035 mm aperture.
High Quality Components
All our systems are constructed using high-quality components sourced from trusted vendors.
